CENTRAL Definition & Meaning

All city busses, trams and metro to all areas of Amsterdam are there, including the bus lines to the north of the city. Amsterdam Ibis Centre, that is built on the station island, is the closest. Through the deregulation of the public transport there are many possibilities to travel on the same train, busses and trams.

Other specified disorders of central nervous system

Trams serve the main city area while busses go farther to the outskirts of the city. With one card you can visit most tourist destinations without other tickets and also use all forms of public transport. For unlimited public transport for tourists we recommend an Amsterdam city pass.

However, these medications also pose many risks.‌‌ When used under the direction of a doctor, CNS depressant medications may improve your quality of life. These medications are prescribed in the form of a pill, capsule, or liquid that you take orally. CNS depressants are an overarching category of medications that include sedatives and hypnotics.

These synonyms and related diagnosis terms are often central nervous system depression used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. WebMD does not provide medical advice, diagnosis or treatment.

  • Voted one of the world’s most walkable cities, Amsterdam’s city centre naturally lends itself to exploration on foot, with so much to discover packed into a compact area.
  • Methadone, quetiapine, divalproex, cyclobenzaprine, fluoxetine, doxepin, and gabapentin were held following this incident due to concerns of repeat CNS depression.
  • As one of the world’s most beautiful cities, there’s no shortage of show-stopping architecture in the city centre, the oldest part of Amsterdam.
  • The patient was taking the combination of methadone, divalproex, gabapentin, and lorazepam from days 8 to 10 without significant adverse effects.

Accessing the station – departures from the Central Station

Or have a rummage at Spui for rare, second-hand and out-of-print books on Fridays and affordable local art on Sundays. A flea market and farmers’ market in one, Noordermarkt is a haven for delicious, organic produce, including honey, cheese and homemade cakes, as well as antiques, books and vintage fashion (Monday mornings and Saturdays). Nieuwmarkt is the place to go for locally-grown fruit and veg on Saturdays, and in the summer, you can haggle for vintage bargains on Sundays.

Amsterdam Trains (from-to)

Upon analyzing the time of administration, dosage, and combination of medications given prior to each adverse event, it was strongly suspected that the combined use of methadone, lorazepam, divalproex, gabapentin, and cyclobenzaprine contributed to opioid toxicity in our patient. On day 11, the patient was found unresponsive 4 hours after administration of her morning medications, which included cyclobenzaprine, divalproex, gabapentin, and methadone. This case of a patient with OUD, mood disorder, and chronic pain suggests avoiding combined use of methadone, lorazepam, divalproex, gabapentin, and cyclobenzaprine or, if required, to use the lowest effective doses with careful monitoring. The need for education on the more judicial use of lorazepam in patients receiving methadone and the preferential use of nonbenzodiazepine supportive medications, such as clonidine, for opioid withdrawal symptoms was identified.11,20 Additionally, the preferential use of buprenorphine/naloxone over methadone in patients requiring benzodiazepines was proposed.

  • Over the weekend, a Chinese central government agency ordered a nationwide inspection of high‑rises.
  • There is also a new tunnel under the station, centrally located Ij-passage which is more of a shopping area because it does not lead to the train platforms but is a convenient way of getting to the lake side of the station.
  • For a hidden surprise, step into the glass elevator, which will take you to Blue Amsterdam – a restaurant with spectacular city views and a menu packed with burgers, light bites and salads – perfect to refuel between shopping.

The reactor sent some radiation into the air over central Pennsylvania. The Bank of Japan governor said the central bank will discuss a rate hike, a comment that lifted the yen and yields on Japanese bonds. Over the weekend, a Chinese central government agency ordered a nationwide inspection of high‑rises. The new bus terminal had been recently added at the back of the station – on so called Ij-zijde (Ij Lake Side).

Swift onset of central nervous system depression and asystole followingan overdose of Guaifenesin

This poses a challenge in the treatment of patients with concurrent psychiatric and substance use disorders as the combined use is often unavoidable. From there, you can easily walk, take a tram, taxi, or bike to your final destination within the city. Just follow the signs for “trains”.

The city ferry boat lines linking the city with Amsterdam North are behind the station at the waterfront (Ij-zijde). The entry to the metro is in front of the station main entrance, on the city centrum side. Taxi services are waiting on the Ij-zijde (waterside) to the left from the Western tunnel thus behind the station looking from the city centre side. Busses and trams are at hand on both sides of the station building but most of them depart on the city side.

Amsterdam Central Station services

Limitations of this case study include the inability to determine causation due to the retrospective nature of the analysis and confounding factors, such as the patient’s clinical status. Informed consent was provided by the patient for the preparation of this case report. CK was elevated (1305 U/L) as it had been from days 7 to 10 and normalized on day 16 (150 U/L). Urine toxicology tested positive to methadone, tricyclic antidepressants, and benzodiazepines.

If you buy a ticket at the vending machine, be careful with your wallet and do care about the secrecy of your PIN identification code. Amsterdam has convenient fast train connections with other European cities as Brussels, Paris and Cologne. Entering the station, you may inquire about the number of the platform you need at the Information desks set inside at the entries to the station. The station has 15 platforms, additionally often divided into “A” and “B” parts. The main entry tunnel as well as the two other tunnels lead you to the station platforms.

Word History and Origins

On day 6, the patient was found unresponsive 3 to 4 hours after the administration of her morning medications. The train station at Schiphol is located directly beneath the airport, and you can buy tickets from the ticket machines or counters located in the arrivals plaza. The journey takes around 15 to 20 minutes by train, which is the most convenient and quickest method of transportation between the airport and the city center. Not chronic – A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. G96.89 is a billable diagnosis code used to specify a medical diagnosis of other specified disorders of central nervous system.

Benefits and Risks of CNS Depressants

Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. Whether you’re looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification. Keep in mind that it may need to be re-administered every 20 minutes until you recover. This medication can offset the overdose symptoms so you can recover.

One dose of naloxone 0.4 mg IM was administered with good response; an increase in RR, BP, and SpO2 were noted, and the patient reported feeling cold, nauseated, and restless. Lorazepam remained available for as-needed use for opioid withdrawal symptoms and anxiety during this time. Methadone was restarted 2 days later (day 8) at 30 mg PO once daily to be titrated by 10 mg each day until at 60 mg daily. Creatinine kinase (CK) was elevated to 907 U/L, which was attributed to the use of physical restraints. She scored 8 (mild withdrawal) on the Clinical Opiate Withdrawal Scale and was given 1 dose of clonidine 0.1 mg and 3 doses of lorazepam 2 mg for withdrawal symptoms.

As one of the world’s most beautiful cities, there’s no shortage of show-stopping architecture in the city centre, the oldest part of Amsterdam. For a hidden surprise, step into the glass elevator, which will take you to Blue Amsterdam – a restaurant with spectacular city views and a menu packed with burgers, light bites and salads – perfect to refuel between shopping. Amsterdam’s city centre is home to many of the Netherlands’ flagship stores, grand department stores, and chic boutiques. Learn a new word every day.

These medications are designed to slow your brain down, relax your muscles, and provide a sense of calm. Finally, the need for increased training on chronic pain and concurrent disorders was discussed. The addition of a naloxone standing order to the psychiatry admission order set was also proposed to increase accessibility to naloxone and to serve as a reminder for nursing staff on how to respond to opioid toxicity. The interaction between lorazepam and divalproex was proposed to be added to the clinical pharmacy software to enhance identification of this potentially serious interaction. This case prompted a retrospective investigation as it is uncommon to have serious, repeated cases of CNS depression requiring naloxone on an inpatient psychiatric unit.

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